Folding Forum

Three Siblings, One Fatal Gene: A Family’s Fight Against Early-Onset Alzheimer’s Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39 By Dominique Mosbergen June 28, 2025 5:30 am ET Hannah Richardson is hopeful about her future and ...

...after a restart or restart after an update, won't pick up GPU-based work units where it left off... 18:41:17:I1: Version: 8.4.9 18:41:17:I1: Author: Joseph Coffland <joseph@cauldrondevelopment.com> 18:41:17:I1: Org: foldingathome.org 18:41:17:I1: Copyright: 2023-2024, foldingathome.org 18:41:17:I...

Appreciate the reply... ...my query was specific to... "...transthyretin amyloid cardiomyopathy, a form of heart failure caused by the liver producing misshaped proteins that form amyloid deposits that stiffen the heart muscle." ...and does F@H contribute to understanding this disease...? ...

A Short Lesson in Drug Competition Calling RFK Jr.: See the new treatment that will break a Pfizer monopoly on a drug for heart disease. By The Editorial Board Nov. 27, 2024 6:42 pm ET Whoever says the Food and Drug Administration is too cozy with Big Pharma isn’t paying attention to the bonanza of ...

The re-install of an older NVIDIA driver seems to have done the trick... We're over 96 hours with no hiccups in operation, so we'll call this one "resolved." What was wrong with the driver/hardware combo? No idea. Why did a previous version of the driver work, and a newer version not work?...

...so after a couple more times with one or both GPUs "Failed," I scuttled the current NVIDIA driver 555.99 and re-installed a much older driver 472.12 (It was the only one I could find) and after 36 hours, things are folding along quite nicely. What prompted me to do that? It was about th...

...a lengthy article describing the use of AI, and particularly DeepMind and AlphaFold(x), to help solve the "protein folding problem." Particular Qs I have... 1. How do F@H and DeepMind projects overlap? 2. How do they differ? --Tom https://www.quantamagazine.org/how-ai-revolutionized-pro...

PS -- I have minimal empirical evidence, but I'm wondering if the problem noted by jchang6 (above, link below) is related.

viewtopic.php?t=41564

--T

"...I wonder which thing you changed was the solution?..." Indeed. It's not clear, or indeed was it a combo of things changed? And the beast has blown off once (both cards "Failed" (Win 11 (current updates) one 1070 and one 3070 (NVIDIA drivers 599.99 - current))) since the gener...

OK, so you know how you never take a car in for servicing until after you get a car wash...? Wellllll... Dis-assembled the PC, blew out everything thoroughly. Re-loaded the NVIDIA drivers v. 599.xx, new download, then clean, complete, from-scratch reload. Coincidentally, Microsoft downloaded an upda...

PPS -- Drivers -- all off the NVIDIA site (always). I think it's 555.xx which is current.

--Tom

You betcha... PS - temps all show <100C, more in the range of 85C - 90C. Tom *********************** Log Started 2024-06-09T21:21:08Z *********************** 21:21:08:******************************* libFAH ******************************** 21:21:08: Date: Oct 20 2020 21:21:08: Time: 13:36:55 21:21:08...

I am getting "Failed" messages on both my GPU's. Everything is stock, no overclocking at all. When I reboot, she'll reload WU(s) and grind on her merry way, until.... Below is my config and the message log. Is it hardware? Software? The WU(s)...? Or worse...insufficient operator intelligen...

...I'll have to check the cost of an upgrade compared to the cost of the subsequent divorce settlement...

--Tom

Following this thread with interest...

I'm seeing the identical issue on an older Intel Quad core 6600 + GTX 750 running Ubuntu 22.04.
I'm wondering if the hardware combo is just plain too old.

Anybody else?

--Tom