Research on sclerosis?

[iceman1992]

Did FAH ever conduct research on sclerosis (ALS, MS, PLS)? It's not on the diseases studied page. I'm wondering if it had previously been studied. Sclerosis seem to be connected with misfolded proteins to some degree (at least some of them).

[Jesse_V]

The term does not occur on folding.stanford.edu nor on folding.typepad.com so IMO its reasonable to assume that no, it does not. And who said sclerosis was affected by protein misfolding? The publication "Neuroligin Trafficking Deficiencies Arising from Mutations in the a/β-Hydrolase Fold Protein Family" in part ties protein misfolding in with autism, but to my knowledge F@h hasn't directly researched that either. However, that doesn't necessarily mean that F@h hasn't impact MS or autism, or tons of other diseases that aren't listed on the Diseases FAQ. Given the amount of times each of the publications from F@h is cited in the scientific community, perhaps one day cures will be found for these diseases based on the foundation of research laid down by F@h and other scientific groups.

Using Google, I found this thread on MS and F@h: viewtopic.php?f=17&t=14726

[iceman1992]

The term does not occur on folding.stanford.edu nor on folding.typepad.com so IMO its reasonable to assume that no, it does not. And who said sclerosis was affected by protein misfolding? The publication "Neuroligin Trafficking Deficiencies Arising from Mutations in the a/β-Hydrolase Fold Protein Family" in part ties protein misfolding in with autism, but to my knowledge F@h hasn't directly researched that either. However, that doesn't necessarily mean that F@h hasn't impact MS or autism, or tons of other diseases that aren't listed on the Diseases FAQ. Given the amount of times each of the publications from F@h is cited in the scientific community, perhaps one day cures will be found for these diseases based on the foundation of research laid down by F@h and other scientific groups.

Using Google, I found this thread on MS and F@h: viewtopic.php?f=17&t=14726

Sorry for the late reply Jesse_V, was out of town a few days.
I found this publication http://www.ncbi.nlm.nih.gov/pubmed/18097159
Yes from what I understand research results about a particular disease can be used in other diseases too?