Did FAH Play A Role In This Promising Development?

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Alan C. Lawhon
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Joined: Thu Dec 20, 2012 3:58 am

Did FAH Play A Role In This Promising Development?

Post by Alan C. Lawhon »

http://phys.org/news/2014-09-scientists ... tml#ajTabs

The article mentions how millions of bioengineered DNA protein variants were tested before they homed in on the decoy protein which demonstrated the greatest affinity for binding to the Gas6 protein - thus greatly reducing metastasis in mice. You don't go looking through "millions" of candidates manually, (or I don't think you do ...), so this seems highly suggestive [to me] that an automated process was used. Since Dr. Cochran and Dr. Giaccia's research involves proteins, I wonder if some of the work units we've been crunching have been runs, clones and gens of projects directly supporting this work?

Hopefully, when the trials and testing move from animals to humans, this new approach won't turn out to be another dead end.
VijayPande
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Joined: Fri Nov 30, 2007 6:25 am
Location: Stanford

Re: Did FAH Play A Role In This Promising Development?

Post by VijayPande »

This is great work, but the WUs didn't support this particular project. We do have a lot going on in cancer in general right now.
Prof. Vijay Pande, PhD
Departments of Chemistry, Structural Biology, and Computer Science
Chair, Biophysics
Director, Folding@home Distributed Computing Project
Stanford University
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