Folding Forum

Project 12137 on FAH! Protein misfolding occurs when a peptide cannot fold into its native structure. Mutations in the protein sequence may cause alterations of the native folded conformation, leading to diseases such as cancer and Alzheimer's. Understanding protein misfolding as a function of mutat...

Projects 12132-6 on FAH! Reflectin-derived peptides hold promise as therapeutic agents due to their unique properties, particularly in the realm of biomedical applications. These peptides, inspired by the reflective capabilities of cephalopods like squid and octopus, exhibit remarkable tunability an...

Projects 12131 on FAH! Protein misfolding occurs when a peptide cannot fold into its native structure. Mutations in the protein sequence may cause alterations of the native folded conformation, leading to diseases such as cancer and Alzheimer's. Understanding protein misfolding as a function of muta...

we don't know if PFAS will ever cause any harm to humans but we keep researching??

That is exactly how science works. How would we find that out without research?

Some recent literature on this:
https://www.nature.com/articles/s41370-024-00742-2

Project 12130 on FAH! Reflectin-derived peptides hold promise as therapeutic agents due to their unique properties, particularly in the realm of biomedical applications. These peptides, inspired by the reflective capabilities of cephalopods like squid and octopus, exhibit remarkable tunability and r...

Project 12129 on FAH! The project involves simulations to assess the conformational diversity of short peptides. More details on - https://stats.foldingathome.org/project/12129 Stats: <timeout v="3"/> <deadline v="5"/> <natoms>285000</natoms> <stats-credit v="476300"/>

Projects 12119, 12120, 12121 on FAH! The projects involve short peptide simulations, which are ideal candidates for studying the conformational dynamics of an exhaustive set of peptide sequences. Insights from these simulations can then be used to design therapeutics and biomaterials. More details h...

Projects 12113,12114 on FAH! Short peptides are considered ideal therapeutics because of their small size and bioactivity, however they are prone to enzyme degradation. Protein Brush Polymers allow peptides to bind to a hydrophobic backbone in a polymeric scheme which enhances the penetration of the...

Projects 12110, 12111, 12112 on FAH! The projects involve short peptide simulations, which are ideal candidates for studying the conformational dynamics of an exhaustive set of peptide sequences. Insights from these simulations can then be used to design therapeutics and biomaterials. These projects...

Projects 12103, 12104, 12105 on FAH! The projects involve short peptide simulations, which are ideal candidates for studying the conformational dynamics of an exhaustive set of peptide sequences. Insights from these simulations can then be used to design therapeutics and biomaterials. These projects...

Projects 12100, 12101, 12102 on FAH! The projects involve short peptide simulations, which are ideal candidates for studying the conformational dynamics of an exhaustive set of peptide sequences. Insights from these simulations can then be used to design therapeutics and biomaterials. More details h...