Folding Forum

Releasing new A7 (GRO_A7) projects p13775-p13778 and p13788, p13789. They are pulling simulations of the enzyme Phenylalanine Hydroylase (PAH), mutations in which cause phenylketonuria (PKU), an inherited disease that affects about 1 in 12000. We are trying to understand the molecular mechanisms by which PAH senses phenylalanine to activate the enzyme. These are similar to project 8617 but pulling one ligand or two ligands from the binding site.
Description here: http://fah-web.stanford.edu/cgi-bin/fah ... ned?p=8617

Projects: 13775
stats credit: 1543
timeout: 23.6
deadline 51.6
k-factor v=0.75
number of atoms: 47340

Projects: 13776
stats credit: 1543
timeout: 23.6
deadline 51.6
k-factor v=0.75
number of atoms: 47340

Projects: 13777
stats credit: 1184
timeout: 18.1
deadline 39.6
k-factor v=0.75
number of atoms: 36217

Projects: 13778
stats credit: 1184
timeout: 18.1
deadline 39.6
k-factor v=0.75
number of atoms: 36217

Projects: 13788
stats credit: 1543
timeout: 23.6
deadline 51.6
k-factor v=0.75
number of atoms: 47340

Projects: 13789
stats credit: 1543
timeout: 23.6
deadline 51.6
k-factor v=0.75
number of atoms: 47340