Moving Projects 9414, 9415, 9431 to Full FAH
Posted: Tue Jan 31, 2017 6:30 pm
Hi all!
I'm releasing projects 9414, 9415, 9431 as a continuation on studies of mutations in p53, a notorious oncoprotein. p53 regulates the cell cycle in response to a variety of molecular signals throughout an organism's development. Mutations of p53 are often associated with disease, most notably cancers, and can completely corrupt the process of apoptosis, or programmed cell death. This study seeks to elucidate the folding mechanism of the disordered C-termini of p53, with the hope of understanding how mutations in this region may affect folding and subsequently proliferate uncontrolled cellular growth.
Happy Folding!
I'm releasing projects 9414, 9415, 9431 as a continuation on studies of mutations in p53, a notorious oncoprotein. p53 regulates the cell cycle in response to a variety of molecular signals throughout an organism's development. Mutations of p53 are often associated with disease, most notably cancers, and can completely corrupt the process of apoptosis, or programmed cell death. This study seeks to elucidate the folding mechanism of the disordered C-termini of p53, with the hope of understanding how mutations in this region may affect folding and subsequently proliferate uncontrolled cellular growth.
Happy Folding!