New A4 project 11644-5 to FAH
Posted: Fri Mar 18, 2016 8:37 pm
These two project are the extension of project 10188-9
viewtopic.php?f=66&t=27264&p=273230&hilit=10188#p273230
Credit: 408
Timeout: 8 days
Deadline: 16 days
This project aims to understand the dynamics of rhodopsin. Rhodopsin is the protein responsible for detecting light in the eye and triggering a signaling cascade that ultimately results in an electrical stimulus that we perceive as an image. Rhodopsin functions by undergoing a conformational change in response to light. Importantly, mutations to rhodopsin can prevent it from having the desired dynamics, resulting in blindness. This project will allow us to study the dynamics of rhodopsin, set a baseline for understanding the negative effects of such mutations, and potentially yield insight into therapeutic strategies for restoring or preventing vision loss.
viewtopic.php?f=66&t=27264&p=273230&hilit=10188#p273230
Credit: 408
Timeout: 8 days
Deadline: 16 days
This project aims to understand the dynamics of rhodopsin. Rhodopsin is the protein responsible for detecting light in the eye and triggering a signaling cascade that ultimately results in an electrical stimulus that we perceive as an image. Rhodopsin functions by undergoing a conformational change in response to light. Importantly, mutations to rhodopsin can prevent it from having the desired dynamics, resulting in blindness. This project will allow us to study the dynamics of rhodopsin, set a baseline for understanding the negative effects of such mutations, and potentially yield insight into therapeutic strategies for restoring or preventing vision loss.