Did FAH Play A Role In This Promising Development?
Posted: Wed Sep 24, 2014 11:22 pm
http://phys.org/news/2014-09-scientists ... tml#ajTabs
The article mentions how millions of bioengineered DNA protein variants were tested before they homed in on the decoy protein which demonstrated the greatest affinity for binding to the Gas6 protein - thus greatly reducing metastasis in mice. You don't go looking through "millions" of candidates manually, (or I don't think you do ...), so this seems highly suggestive [to me] that an automated process was used. Since Dr. Cochran and Dr. Giaccia's research involves proteins, I wonder if some of the work units we've been crunching have been runs, clones and gens of projects directly supporting this work?
Hopefully, when the trials and testing move from animals to humans, this new approach won't turn out to be another dead end.
The article mentions how millions of bioengineered DNA protein variants were tested before they homed in on the decoy protein which demonstrated the greatest affinity for binding to the Gas6 protein - thus greatly reducing metastasis in mice. You don't go looking through "millions" of candidates manually, (or I don't think you do ...), so this seems highly suggestive [to me] that an automated process was used. Since Dr. Cochran and Dr. Giaccia's research involves proteins, I wonder if some of the work units we've been crunching have been runs, clones and gens of projects directly supporting this work?
Hopefully, when the trials and testing move from animals to humans, this new approach won't turn out to be another dead end.