Projects 10021-24, 10027, 10030-34, 10038-39
Posted: Thu Apr 29, 2010 8:51 pm
Projects 10021-24, 10027, 10030-34, 10038-39 using the new ProtoMol core have just entered advanced methods
WARNING
We're using core version 23. A known issue is that killing and restarting the client forces the simulation to restart. We're working to address this problem.
These are all WW domain mutants. We now have 21 mutants running as separate projects. The goal is to gain further insight into the effect these mutations have on folding. Hopefully the simulations will match the predictions in the referenced paper.
points: 126
timeout: 4.6 days
deadline: 34.5 days
Reference:
"An experimental survey of the transition between two-state and downhill protein folding scenarios"
Feng Liu, Deguo Du, Amelia A. Fuller, Jennifer E. Davoren, Peter Wipf, Jeffery W. Kelly, and Martin Gruebele
PNAS February 19, 2008 vol. 105 no. 7 2369-2374
WARNING
We're using core version 23. A known issue is that killing and restarting the client forces the simulation to restart. We're working to address this problem.
These are all WW domain mutants. We now have 21 mutants running as separate projects. The goal is to gain further insight into the effect these mutations have on folding. Hopefully the simulations will match the predictions in the referenced paper.
points: 126
timeout: 4.6 days
deadline: 34.5 days
Reference:
"An experimental survey of the transition between two-state and downhill protein folding scenarios"
Feng Liu, Deguo Du, Amelia A. Fuller, Jennifer E. Davoren, Peter Wipf, Jeffery W. Kelly, and Martin Gruebele
PNAS February 19, 2008 vol. 105 no. 7 2369-2374